Diclofenac Sodium – Uses, Side Effects, and More

Diclofenac sodium is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to relieve pain, reduce inflammation, and manage various medical conditions. Here is an overview of its uses, side effects, and other important information:


  1. Pain Relief: Diclofenac is often prescribed to relieve pain from various sources, including musculoskeletal injuries, osteoarthritis, rheumatoid arthritis, and other inflammatory conditions.
  2. Inflammation Reduction: It is used to reduce inflammation associated with conditions like arthritis, bursitis, and tendinitis.
  3. Fever Reduction: Diclofenac can help lower fever in some cases.
  4. Migraine Headache Relief: It is sometimes used to manage migraine headaches.

Dosage: The dosing of diclofenac sodium can vary depending on the specific condition being treated. It is available in various forms, including oral tablets, capsules, topical gels or creams, and in some regions, as an injectable solution. Dosage and duration of treatment should be determined by a healthcare provider, and it’s crucial to follow their instructions carefully.

Common Side Effects:

  • Stomach upset or pain
  • Nausea and vomiting
  • Diarrhea
  • Headache
  • Dizziness
  • Skin rash

Serious Side Effects (Rare): Diclofenac sodium can lead to more severe side effects, including but not limited to:

  • Gastrointestinal bleeding or ulcers, which can be life-threatening.
  • Allergic reactions, such as rash, itching, swelling, severe dizziness, and difficulty breathing.
  • Liver problems, which can manifest as yellowing of the skin or eyes (jaundice), dark urine, or persistent nausea.
  • Kidney problems, including changes in urine color or frequency.


  • Diclofenac should be used with caution in individuals with a history of stomach or intestinal issues, as it can increase the risk of gastrointestinal bleeding.
  • Long-term use or high doses of diclofenac may increase the risk of cardiovascular events, such as heart attack or stroke.
  • It’s important to inform your healthcare provider about any pre-existing medical conditions, other medications, or supplements you are taking, as these can interact with diclofenac.
  • Diclofenac should not be used in the last trimester of pregnancy as it may harm the developing fetus. It can also pass into breast milk, so its use while breastfeeding should be discussed with a healthcare provider.

Drug Interactions: Diclofenac sodium can interact with various medications, including blood thinners, other NSAIDs, and certain blood pressure medications. Always inform your healthcare provider about all the medications you are taking to avoid potential interactions.

This information is a general overview of diclofenac sodium. It’s essential to consult with a healthcare professional for specific guidance and recommendations tailored to your individual health needs and circumstances. Additionally, it’s important to use this medication as prescribed and not to exceed the recommended dose or duration of use.